AI-Driven Neoantigen Discovery & TCR Screening

Our integrated computational and experimental framework is designed to accelerate target discovery and validation for next-generation T cell-based immunotherapies. By combining AI-driven analytics with advanced screening technologies, we enable the rapid identification of clinically relevant antigens and TCR candidates for personalized and off-the-shelf therapeutic development.

AI-Based Neoantigen Prediction Platform

  • Proprietary pMHC binding prediction and immunogenicity scoring

  • Patient-specific neoantigen pipelines integrated with NGS

TCR Library Screening

  • High-throughput TCR sequencing and epitope mapping

  • TCR-pMHC binding assays and cytotoxicity validation

Functional Validation of TCR Candidates

  • TCR-engineered T cell generation and tumor killing assays

  • In vivo validation using humanized or syngeneic mouse models