Human IL-21
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Interleukin-21 (IL-21) is a cytokine produced mainly by T follicular helper cells and certain innate lymphoid cells, regulating immune responses by promoting B cell differentiation, antibody production, and T cell activation. It also enhances NK cell activity and plays a crucial role in germinal center formation and inflammation modulation.
Recombinant human IL-21 is used in research to study immune regulation, cell-mediated immunity, and to develop targeted treatments for autoimmune diseases, cancer, and chronic infections.
| Cat. No. | RC0021 |
|---|---|
| Purity | >95% in SDS-PAGE followed by coomassie staining |
| Endotoxin Level | <0.01 EU/µg (LAL Assay) |
| Source | Purified from the culture supernatant of HEK 293 cells genetically engineered to express human IL-21 protein with a C-terminal His tag. |
| Accession # | NP_068575 |
| Applications/Intended Use | Research Use Only: This product is intended for laboratory research use only. It is not intended for any animal or human therapeutic use, any human or animal consumption, or any diagnostic use. |
| Molecular Mass | Predicted mass (14.8 kDa), appears 17 - 43 kDa due to glycosylation |
| Formulation | Lyophilized from a 0.1 μm filtered solution in PBS with Trehalose |
| Reconstitution | Dissolve in sterile PBS to 0.1-0.5 mg/mL or user preferred stock concentration. |
| Shipping or Handling Information | Shipped at ambient temperature |
| CoA | Batch-specific test results will be provided with the product |
| Stability | Lyophilized: Stable for 12 months at -80°C; Reconstituted: Stable for 2 weeks at 4°C, or 3-6 months at -20°C |
| Disclaimer | All of TME Scientific cell biology products are for research use ONLY and NOT for therapeutic/diagnostic applications. TME Scientific is not liable for any repercussions arising from the use of its cell biology product(s) in therapeutic/diagnostic or any other non-RUO application(s). |
